内分泌系统 英文版【2025|PDF|Epub|mobi|kindle电子书版本百度云盘下载】

内分泌系统 英文版PDF格式电子书版下载

注意：本站所有压缩包均有解压码： 点击下载压缩包解压工具

1 INTRODUCTION1

What is endocrinology？2

What do hormones do？2

Types of hormone：their synthesis and secretion4

The transport and metabolism of hormones7

Important concepts in endocrine regulation8

Endocrine disorders10

Endocrine investigations：general principles12

2 RECEPTORS AND HORMONE ACTION15

Introduction16

General characteristics of receptors16

Types of hormone receptors17

Cell-membrane receptors17

Hormonal regulation of transcription23

Intracellular receptors24

Disorders of receptor function26

3 THE HYPOTHALAMUS AND PITUITARY PART Ⅰ：THE HYPOTHALAMUS AND POSTERIOR PITUITARY27

Introduction28

Where can I find the hypothalamus and pituitary？28

Connection between the hypothalamus and pituitary31

Development of the hypothalamus and pituitary31

The hormones of the hypothalamus31

The hormones of the posterior pituitary32

Release of posterior pituitary hormones is part of a neuroendocrine reflex：oxytocin secretion and actions32

Regulation of vasopressin secretion33

Actions of arginine vasopressin34

Disorders of vasopressin secretion and action35

Thirst36

Other hypothalamic hormones37

4 THE HYPOTHALAMUS AND PITUITARY PART Ⅱ:THE ANTERIOR PITUITARY39

Introduction40

Structure of the anterior pituitary40

The hormones of the anterior pituitary41

Regulation of hormone secretion in the anterior pituitary43

Growth hormone and prolactin in blood46

Actions of the anterior pituitary hormones growth：hormone and prolactin46

Disorders of anterior pituitary function：over-secretion48

Disorders of under-secretion of anterior pituitary hormones49

Tests for hypopituitarism50

Insufficient growth hormone secretion50

5 THE ADRENAL GLANDS PART Ⅰ：THE ADRENAL MEDULLA53

Introduction54

Where to find the adrenal glands54

Blood supply54

Nerve supply55

Embryology of the adrenal gland55

The adrenal medulla55

Disorders of the adrenal medulla：phaeochromocytoma59

Familial phaeochromocytoma59

Pharmacological uses of hormones of the adrenal medulla60

6 THE ADRENAL GLANDS PART Ⅱ:THE ADRENAL CORTEX61

Introduction62

Structure of the adrenal cortex62

Hormones produced by the adrenal cortex62

Regulation of steroid production66

Transport of steroid hormones in blood68

Disorders of adrenal steroids71

Pharmacological use of glucocorticoids73

7 THE THYROID GLAND75

Introduction76

Thyroid anatomy77

Whatis a goitre？77

Blood supply77

Structure of the thyroid78

Synthesis of thyroid hormones78

Iodine79

Thyroxine and T3：the thyroid hormones in blood79

Control of thyroid function81

Cellular action of thyroid hormones82

Effects of thyroid hormones82

Disorders of thyroid hormone secretion83

Causes of thyroid hyposecretion85

Effects of thyroid hormone insufficiency：myxoedema85

8 HORMONAL CONTROL OF REPRODUCTION PART Ⅰ：MALE REPRODUCTIVE SYSTEM87

Introduction88

Where are the testes？88

What are the testes？89

Testicular blood and nerve supply90

Spermatogenesis91

Androgen production91

Hormonal control of testicular function91

Transport of testosterone in blood93

Actions of testosterone93

Hormone-dependent cancer in men95

Disorders of male reproduction96

Therapeutic uses of androgens97

Abuse of anabolic androgenic steroids97

Declining sperm counts98

9 HORMONAL CONTROL OF REPRODUCTION PART Ⅱ:FEMALE REPRODUCTIVE SYSTEM99

Introduction100

Structure of the ovary100

Ovarian hormones100

Transport and metabolism of oestrogen and progesterone102

Oestrogens102

Androgen secretion by the ovaries104

Hormonal regulation of ovarian function105

Hormone-dependent cancer in women105

The menstrual cycle105

Disorders of the menstrual cycle108

The endocrinology of pregnancy110

10 HORMONAL CONTROL OF REPRODUCTION PART Ⅲ:DEVELOPMENT AND FERTILITY115

Introduction116

Gender determination and differentiation116

Hormonal control of sexual differentiation116

Abnormalities of sexual differentiation117

Hormones during development：puberty and menarche118

Disorders of puberty119

Menopause and the climacteric121

Premature ovarian failure122

Symptoms of the menopause122

Hormone replacement therapy123

Alternative therapies125

Hormonal control of fertility：contraception125

Hormonal control of fertility：assisted conception126

11 INSULIN AND THE REGULATION OF PLASMA GLUCOSE129

Introduction130

Glucose in urine130

Insulin and the response to high blood glucose levels131

Disorders of blood glucose regulation：diabetes mellitus135

Gestational diabetes143

The metabolic syndrome—a growing problem？143

12 HORMONAL REGULATION OF PLASMA CALCIUM AND CALCIUM METABOLISM147

Introduction148

Serum calcium148

The structure,functions and endocrinology of bone149

Hormones involved in the regulation of serum calcium151

Parathyroid hormone151

Calcitriol：source and activation of vitamin D153

Effects of other hormones on plasma calcium156

Disorders of hypercalcaemia156

Disorders of hypocalcaemia157

Diseases of bone158

A brief mention of calcitonin159

Regulation of serum phosphate159

13 MISCELLANEOUS HORMONES161

Erythropoietin162

Immune-endocrine interactions：cytokines and eicosanoids163

Age-related changes in hormone secretion164

Melatonin164

Gut hormones166

The hormonal control of appetite：fat is an endocrine tissue167

Multiple organ disorders in endocrinology168

Regulation of blood pressure and volume169

The next 100 years of endocrinology169

Glossary171

Index173